The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 25, 2010

Filed:

Jun. 15, 2005
Applicants:

Mingxian Huang, San Diego, CA (US);

David Rothwarf, La Jolla, CA (US);

Jia Xu, San Diego, CA (US);

Xiaobo Wang, San Diego, CA (US);

Lei Wu, San Diego, CA (US);

Antonio Guia, San Diego, CA (US);

Inventors:

Mingxian Huang, San Diego, CA (US);

David Rothwarf, La Jolla, CA (US);

Jia Xu, San Diego, CA (US);

Xiaobo Wang, San Diego, CA (US);

Lei Wu, San Diego, CA (US);

Antonio Guia, San Diego, CA (US);

Assignee:

Aviva Biosciences Corporation, San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention recognizes that the determination of an ion transport function or property using direct detection methods, such as patch-clamps, whole cell recording or single channel recording, are preferable to methods that utilize indirect detection methods, such as FRET based detection system. The present invention provides biochips and methods of use that allow for the direct analysis of ion transport functions or properties using microfabricated structures that can allow for automated detection of one or more ion transport functions or properties. These biochips and methods of use thereof are particularly appropriate for automating the detection of ion transport functions or properties, particularly for screening purposes.


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