The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 25, 2010
Filed:
Feb. 09, 2006
Sudhir V. Shah, Little Rock, AR (US);
Alexei G. Basnakian, Little Rock, AR (US);
Yousri M. Barri, Richardson, TX (US);
Sudhir V. Shah, Little Rock, AR (US);
Alexei G. Basnakian, Little Rock, AR (US);
Yousri M. Barri, Richardson, TX (US);
Board of Trustees of the University of Arkansas, Little Rock, AR (US);
The United States of America as represented by the Department of Veterans Affairs, Washington, DC (US);
Abstract
The present invention provides a method of determining whether an individual is at risk for atherosclerosis, comprising the step of measuring the level of cLDL and/or autoantibody to cLDL in a sample obtained from this individual. The invention further discloses a method of reducing carbamylation in an individual with a monomeric amino acid or other enzymatic or non-enzymatic inhibitors of carbamylation. The instant invention also provides a method to decrease the level of cLDL by direct elimination of cLDL from the blood or plasma of an individual. The invention also provides a method of treating or preventing atherosclerosis in an individual by inhibiting aggregation and/or deposition of cLDL in the individual.