The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 18, 2010

Filed:

Jul. 25, 2007
Applicants:

Jae Hyun Kim, Seoul, KR;

Su Kyung Lee, Chungcheongnam-do, KR;

Won Kyu Choi, Seoul, KR;

Jong Lae Lim, Chungcheongnam-do, KR;

Soon Kil Ahn, Seoul, KR;

Hee Jong Shin, Kyunggi-do, KR;

Chung IL Hong, Chicago, IL (US);

Inventors:

Jae Hyun Kim, Seoul, KR;

Su Kyung Lee, Chungcheongnam-do, KR;

Won Kyu Choi, Seoul, KR;

Jong Lae Lim, Chungcheongnam-do, KR;

Soon Kil Ahn, Seoul, KR;

Hee Jong Shin, Kyunggi-do, KR;

Chung Il Hong, Chicago, IL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/336 (2006.01); C07D 303/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to an inclusion compound of fumagillol derivative or its salt with hydroxypropyl-β-cyclodextrin or sulfobutylether-7-β-cyclodextrin, and pharmaceutical compositions comprising the same. The inclusion compound according to the present invention has superior water solubility and stability while exhibiting low toxicity, rendering it valuable as an anticancer agent or inhibitor of tumor metastasis.


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