The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 18, 2010
Filed:
Jul. 08, 2004
Avinash Phadke, Branford, CT (US);
Jesse Quinn, Windsor, CT (US);
Junko Ohkanda, Gakuennishi, JP;
Andrew Thurkauf, Ridgefield, CT (US);
Yiping Shen, Branford, CT (US);
Cuixian Liu, Branford, CT (US);
Dawei Chen, Middletown, CT (US);
Shouming LI, Cheshire, CT (US);
Xiangzhu Wang, Branford, CT (US);
Avinash Phadke, Branford, CT (US);
Jesse Quinn, Windsor, CT (US);
Junko Ohkanda, Gakuennishi, JP;
Andrew Thurkauf, Ridgefield, CT (US);
Yiping Shen, Branford, CT (US);
Cuixian Liu, Branford, CT (US);
Dawei Chen, Middletown, CT (US);
Shouming Li, Cheshire, CT (US);
Xiangzhu Wang, Branford, CT (US);
Achillion Pharmaceuticals, Inc., New Haven, CT (US);
Abstract
Substituted arylthiourea compounds of Formula I, and the pharmaceutically acceptable salts of such compounds, useful as antiviral agents, are provided herein. Certain substituted arylthioureas disclosed herein are potent and/or selective inhibitors of viral replication, particularly Hepatitis C virus replication. Pharmaceutical compositions containing one or more substituted arylthiourea compounds and one or more pharmaceutically acceptable carriers, excipients, or diluents are provided herein. Such pharmaceutical compositions may contain a substituted arylthiourea as the only active agent or may contain a combination of a substituted arylthiourea derivative and one or more other pharmaceutically active agents. Methods of treating Hepatitis C viral infections in mammals are also provided herein.