The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 18, 2010
Filed:
Dec. 22, 2008
John Anderson, San Francisco, CA (US);
Lisa Mcconlogue, Burlingame, CA (US);
Guriqbal Basi, Palo Alto, CA (US);
Sukanto Sinha, San Francisco, CA (US);
John Anderson, San Francisco, CA (US);
Lisa McConlogue, Burlingame, CA (US);
Guriqbal Basi, Palo Alto, CA (US);
Sukanto Sinha, San Francisco, CA (US);
Elan Pharmaceuticals, Inc., South San Francisco, CA (US);
Abstract
Human BACE polypeptides having modifications to the N-linked glycosylation sites including one or more of the following amino acid substitutions: S174I, N223A, N153Q and N354S. DNA sequences, vectors, and host cells for producing the polypeptides. Crystalline protein compositions formed from the purified polypeptides. Methods of screening for compounds that inhibit Aβ using the polypeptides.