The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 18, 2010
Filed:
Dec. 06, 2002
Applicants:
Hugo Ziegler, Witterswil, CH;
Dagmar Prasa, Erfurt, DE;
Jörg Stürzebecher, Erfurt, DE;
Peter Wikstroem, Gipf-Oberfrick, CH;
Inventors:
Hugo Ziegler, Witterswil, CH;
Dagmar Prasa, Erfurt, DE;
Jörg Stürzebecher, Erfurt, DE;
Peter Wikstroem, Gipf-Oberfrick, CH;
Assignee:
DSM IP Assets B.V., Heerlen, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 13/04 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention relates to compounds of general formula (I) and acid addition salts thereof, where the various symbols have the meanings given in the description and claims, the production and use thereof as substrate for the detection of TAFIa, a fibrinolysis inhibiting enzyme. The detection occurs by using the absorption between 400 and 412 nm, arising as a result of the formation of 3-carboxy-4-nitrothiophenol from Ellman's reagent as a function of time.