The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 18, 2010

Filed:

Mar. 25, 2004
Applicants:

Dave S. B. Hoon, Los Angeles, CA (US);

Bret Taback, Santa Monica, CA (US);

Inventors:

Dave S. B. Hoon, Los Angeles, CA (US);

Bret Taback, Santa Monica, CA (US);

Assignees:

John Wayne Cancer Institute, Santa Monica, CA (US);

Other;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C11Q 1/68 (2006.01); C07H 21/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method is provided for assessing allelic losses and hypermethylation of genes in CpG tumor promotor region on specific chromosomal regions in cancer patients, including melanoma, neuroblastoma breast, colorectal, and prostate cancer patients. The method relies on the evidence that free DNA and hypermethylation of genes in CpG tumor promotor region may be identified in the bone marrow, serum, plasma, and tumor tissue samples of cancer patients. Methods of melanoma, neuroblastoma, colorectal cancer, breast cancer and prostate cancer detection, staging, and prognosis are also provided.


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