The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 11, 2010

Filed:

Jun. 18, 2002
Applicants:

Robert O. Dempcy, Kirkland, WA (US);

Alexander A. Gall, Woodland, WA (US);

Sergey G. Lokhov, Kirkland, WA (US);

Irina A. Afonina, Mill Creek, WA (US);

Michael J. Singer, Seattle, WA (US);

Karen M. Singer, Legal Representative, Seattle, WA (US);

Igor V. Kutyavin, Woodinville, WA (US);

Nicolaas M. J. Vermeulen, Woodinville, WA (US);

Inventors:

Robert O. Dempcy, Kirkland, WA (US);

Alexander A. Gall, Woodland, WA (US);

Sergey G. Lokhov, Kirkland, WA (US);

Irina A. Afonina, Mill Creek, WA (US);

Michael J. Singer, Seattle, WA (US);

Karen M. Singer, legal representative, Seattle, WA (US);

Igor V. Kutyavin, Woodinville, WA (US);

Nicolaas M. J. Vermeulen, Woodinville, WA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/48 (2006.01);
U.S. Cl.
CPC ...
Abstract

Software systems and methods for predicting the melting temperature (Tm) and other characteristics of oligonucleotides, including modified oligonucleotides. Modified oligonucleotides are provided containing bases selected from unsubstituted and 3-substituted pyrazolo[3,4-d]pyrimidines and 5-substituted pyrimidines, and optionally have attached minor groove binders and reporter groups.


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