The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 11, 2010
Filed:
May. 08, 2003
Yoram Salomon, Rehovot, IL;
Michal Neeman, Mazkeret Batya, IL;
Avigdor Scherz, Rehovot, IL;
Shimon Gross, Rehovot, IL;
Assaf Gilead, Haifa, IL;
Yoram Salomon, Rehovot, IL;
Michal Neeman, Mazkeret Batya, IL;
Avigdor Scherz, Rehovot, IL;
Shimon Gross, Rehovot, IL;
Assaf Gilead, Haifa, IL;
Yeda Research and Development Co. Ltd., Rehovot, IL;
Abstract
An online Blood Oxygenation Level-Dependent (BOLD)-magnetic resonance imaging (MRI) method for functional clinical guidance or monitoring a therapeutic modality involving treatment by a sensitizer which, upon excitation by the appropriate sensitizing radiation, initiates local oxygen consumption, comprising: (i) generating a BOLD-weighted MR-image of the target region of interest within the patient's body (time t); (ii) administering said sensitizer to the patient; (iii) irradiating the target region while the patient is subjected to continuous MR imaging; (iv) generating a sole or a plurality of T2* weighted sequential BOLD MR-images during and/or after irradiation (time t); (v) processing the data generated at time tand time t and generating a color-coded difference or ratio map on a pixel by pixel basis; and (vi) analyzing the processed data. The method is preferably applied to photodynamic therapy (PDT).