The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 11, 2010

Filed:

Mar. 24, 2005
Applicants:

I. Fraser Pickersgill, Newton, PA (US);

John E. Bishop, Groton, MA (US);

Christoph Koellner, Bubendorf, CH;

Jean-marc Gomez, Bubendorf, CH;

Achim Geiser, Hunzenschwil, CH;

Robert Hett, Hunzenschwil, CH;

Inventors:

I. Fraser Pickersgill, Newton, PA (US);

John E. Bishop, Groton, MA (US);

Christoph Koellner, Bubendorf, CH;

Jean-Marc Gomez, Bubendorf, CH;

Achim Geiser, Hunzenschwil, CH;

Robert Hett, Hunzenschwil, CH;

Assignee:

Millennium Pharmaceuticals, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 558/288 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.


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