The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 11, 2010
Filed:
May. 30, 2006
Yukiyoshi Yamazaki, Higashimurayama, JP;
Takaaki Araki, Higashimurayama, JP;
Minoru Koura, Kawagoe, JP;
Kimiyuki Shibuya, Tokorozawa, JP;
Yukiyoshi Yamazaki, Higashimurayama, JP;
Takaaki Araki, Higashimurayama, JP;
Minoru Koura, Kawagoe, JP;
Kimiyuki Shibuya, Tokorozawa, JP;
Kowa Co., Ltd., Nagoya-shi, JP;
Abstract
The invention provides a process for producing an optically active butyric acid compound and a production intermediate therefore at high yield and high purity. The present invention provides a process for producing Compound (6), including reacting Compound (1) with optically active 2-trifluoromethanesulfonyloxybutyrolactone (2) in the presence of a base or reacting optically active 2-hydroxybutyrolactone (2) under Mitsunobu reaction conditions, to thereby form Compound (3); reacting Compound (3) with an alcohol and a halogenating agent, to thereby form Compound (4); dehalogenating Compound (4), to thereby form Compound (5); and de-esterifying Compound (5).