The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 11, 2010
Filed:
Aug. 26, 2003
Miroslav Veverka, Bratislava, SK;
Stefan Vodny, Bratislava, SK;
Eva Veverkova, Bratislava, SK;
Josef Hajicek, Prague, CZ;
Hana Stepankova, Cesky Brod, CZ;
Miroslav Veverka, Bratislava, SK;
Stefan Vodny, Bratislava, SK;
Eva Veverkova, Bratislava, SK;
Josef Hajicek, Prague, CZ;
Hana Stepankova, Cesky Brod, CZ;
Zentiva, k.s., Prague, CZ;
Abstract
A method for manufacturing hydrogen sulphate (alpha S) of the alpha-(2-chlorophenyl)-6,7dihydrothieno[3,2-c]pyridine-5(4H)-acetic acid methyl ester (clopidogrel hydrogen sulphate) of formula I, in crystalline Form I, wherein the compound of formula is separated out of a solution of clopidogrel in the form of the free base or salt in a solvent selected from the series of primary, secondary or tertiary C1-C5 alcohols, their esters with C1-C4 carboxylic acids, or optionally of mixtures thereof.