The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 11, 2010
Filed:
Oct. 21, 2005
Carina Engstrand, Uppsala, SE;
Annika Forss, Uppsala, SE;
Gunnar Glad, Uppsala, SE;
Bo-lennart Johansson, Uppsala, SE;
Hans J. Johansson, Uppsala, SE;
Jean-luc Maloisel, Uppsala, SE;
Carina Engstrand, Uppsala, SE;
Annika Forss, Uppsala, SE;
Gunnar Glad, Uppsala, SE;
Bo-Lennart Johansson, Uppsala, SE;
Hans J. Johansson, Uppsala, SE;
Jean-Luc Maloisel, Uppsala, SE;
GE Healthcare Bio-Sciences AB, Uppsala, SE;
Abstract
The present invention relates to a method of separating antibodies from other compound(s) in a liquid sample, wherein a mobile phase comprising said sample is contacted with a multi-modal separation matrix to adsorb undesired compounds while the antibodies remain free in the liquid, wherein the multi-modal separation matrix comprises first groups, which are capable of interacting with negatively charged sites of the target compounds, and second groups, which are capable of at least one interaction other than charge-charge interaction with said target compounds. The invention also relates to a chromatography column packed with the above-described multi-modal separation matrix and a filter having such multi-modal groups adsorbed to its surface.