The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 11, 2010

Filed:

Oct. 26, 2005
Applicants:

Thomas Daniel Aicher, Superior, CO (US);

Mark Joseph Chicarelli, Longmont, CO (US);

Ronald Jay Hinklin, Longmont, CO (US);

Hongqi Tian, Longmont, CO (US);

Owen Brendan Wallace, Zionsville, IN (US);

John Gordon Allen, Newbury Park, CA (US);

Zhaogen Chen, Shanghai, CN;

Thomas Edward Mabry, Indianapolis, IN (US);

Jefferson Ray Mccowan, Indianapolis, IN (US);

Nancy June Snyder, Lizton, IN (US);

Leonard Larry Winneroski, Jr., Greenwood, IN (US);

Inventors:

Thomas Daniel Aicher, Superior, CO (US);

Mark Joseph Chicarelli, Longmont, CO (US);

Ronald Jay Hinklin, Longmont, CO (US);

Hongqi Tian, Longmont, CO (US);

Owen Brendan Wallace, Zionsville, IN (US);

John Gordon Allen, Newbury Park, CA (US);

Zhaogen Chen, Shanghai, CN;

Thomas Edward Mabry, Indianapolis, IN (US);

Jefferson Ray McCowan, Indianapolis, IN (US);

Nancy June Snyder, Lizton, IN (US);

Leonard Larry Winneroski, Jr., Greenwood, IN (US);

Assignee:

Eli Lilly and Company, Indianapolis, IN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 207/00 (2006.01); A61K 31/40 (2006.01); A61K 31/497 (2006.01); A61K 31/445 (2006.01); C07D 211/06 (2006.01); C07D 403/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention discloses compounds of Formula I: (I) having 11beta-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as the use of the Formula I and compositions as medicaments to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, Syndrome X, and other conditions associated with hyperglycemia.


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