The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 11, 2010
Filed:
Dec. 08, 1998
Applicants:
Jean Gariepy, Toronto, CA;
Mark Robert Bray, Toronto, CA;
Inventors:
Jean Gariepy, Toronto, CA;
Mark Robert Bray, Toronto, CA;
Assignee:
Molecular Templates, Inc., Georgetown, TX (US);
Primary Examiner:
Int. Cl.
CPC ...
C40B 20/01 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
Abstract
A method is provided for constructing, identifying and using new therapeutic or diagnostic proteins capable of binding to a target cell. The new proteins are derived by mutating a binding subunit of a wild type heteromeric cytotoxic protein to create a library of microorganism clones producing mutant proteins which are then screened for their ability to specifically bind to and kill a target cell.