The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 11, 2010
Filed:
Aug. 31, 2007
John N. Feder, Belle Mead, NJ (US);
Thomas C. Nelson, Lawrenceville, NJ (US);
Chandra S. Ramanathan, Ringoes, NJ (US);
Rolf-peter Ryseck, Ewing, NJ (US);
Michael G. Kornacker, Princeton, NJ (US);
John N. Feder, Belle Mead, NJ (US);
Thomas C. Nelson, Lawrenceville, NJ (US);
Chandra S. Ramanathan, Ringoes, NJ (US);
Rolf-Peter Ryseck, Ewing, NJ (US);
Michael G. Kornacker, Princeton, NJ (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
The present invention provides novel polynucleotides encoding HGPRBMY23 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel HGPRBMY23 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, particularly renal diseases and/or disorders, colon cancer, breast cancer, and diseases and disorders related to aberrant NFKB modulation. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.