The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 04, 2010

Filed:

Jan. 28, 2008
Applicants:

William Gaarde, Carlsbad, CA (US);

Andrew T Watt, Oceanside, CA (US);

Brett P Monia, Encinitas, CA (US);

Mausumee Guha, Trabuco Canyon, CA (US);

Inventors:

William Gaarde, Carlsbad, CA (US);

Andrew T Watt, Oceanside, CA (US);

Brett P Monia, Encinitas, CA (US);

Mausumee Guha, Trabuco Canyon, CA (US);

Assignee:

ISIS Pharmaceuticals, Inc., Carlsbad, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C07H 21/02 (2006.01); A61K 31/70 (2006.01); C12Q 1/68 (2006.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Antisense compounds, compositions and methods are provided for modulating the expression of connective tissue growth factor. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding connective tissue growth factor. Methods of using these compounds for modulation of connective tissue growth factor expression and for treatment of diseases associated with expression of connective tissue growth factor are provided.


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