The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 04, 2010
Filed:
Jul. 15, 2004
Reiko Irie, Pacific Palisades, CA (US);
Hiroyuki Tsunoda, Ibaraki, JP;
Tomoyuki Igawa, Shizuoka, JP;
Yasuo Sekimori, Shizuoka, JP;
Masayuki Tsuchiya, Shizuoka, JP;
Reiko Irie, Pacific Palisades, CA (US);
Hiroyuki Tsunoda, Ibaraki, JP;
Tomoyuki Igawa, Shizuoka, JP;
Yasuo Sekimori, Shizuoka, JP;
Masayuki Tsuchiya, Shizuoka, JP;
Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;
Abstract
IgM can be obtained in the form of a pentamer by placing the genes encoding the H, L, and J chains on the same vector to transform appropriate host cells. The gene encoding the J chain may be introduced by co-transfection. When no J chain is expressed, the IgM is produced as a hexamer. The transformants obtained according to the present invention achieve a high yield of IgM. The present invention also provides methods which enable separation and quantification of polymeric IgM.