The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 04, 2010

Filed:

May. 30, 2006
Applicants:

Jonathan Zalevsky, Riverside, CA (US);

Duc-hanh Thi Nguyen, Sylmar, CA (US);

Gregory L. Moore, Monrovia, CA (US);

Sergei A. Ezhevsky, San Diego, CA (US);

John R. Desjarlais, Pasadena, CA (US);

Arthur J. Chirino, Camarillo, CA (US);

Darian Cash, Los Angeles, CA (US);

Matthew J. Bernett, Monrovia, CA (US);

Inventors:

Jonathan Zalevsky, Riverside, CA (US);

Duc-Hanh Thi Nguyen, Sylmar, CA (US);

Gregory L. Moore, Monrovia, CA (US);

Sergei A. Ezhevsky, San Diego, CA (US);

John R. Desjarlais, Pasadena, CA (US);

Arthur J. Chirino, Camarillo, CA (US);

Darian Cash, Los Angeles, CA (US);

Matthew J. Bernett, Monrovia, CA (US);

Assignee:

Xencor, Inc., Monrovia, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 1/00 (2006.01); C07K 14/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01); A61K 38/24 (2006.01); A61K 38/27 (2006.01);
U.S. Cl.
CPC ...
Abstract

An adiponectin variant with one or more amino acid modifications relative to a corresponding parent adiponectin, wherein the solubility of the variant is improved by at least 3-fold relative to residues 110-244 of human adiponectin.


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