The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 04, 2010
Filed:
Feb. 19, 2002
Thomas Arrhenius, Del Mar, CA (US);
Jie Fei Cheng, Carlsbad, CA (US);
Mark E. Wilson, Ramona, CA (US);
Rossy Serafimov, Metz, FR;
Alex M. Nadzan, Encinitas, CA (US);
Gary D. Lopaschuk, Edmonton, CA;
Jason R. Dyck, Sherwood Park, CA;
Thomas Arrhenius, Del Mar, CA (US);
Jie Fei Cheng, Carlsbad, CA (US);
Mark E. Wilson, Ramona, CA (US);
Rossy Serafimov, Metz, FR;
Alex M. Nadzan, Encinitas, CA (US);
Gary D. Lopaschuk, Edmonton, CA;
Jason R. Dyck, Sherwood Park, CA;
Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;
Abstract
The present invention relates to methods of treatment of certain metabolic diseases, and to novel compounds and their prodrugs, and/or pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds useful in treating such diseases. In particular, this invention relates to the use of novel compounds and compositions for treatment of cardiovascular diseases, diabetes, cancers, acidosis, and obesity through the inhibition of malonyl-CoA decarboxylase (MCD). These compounds have the formulae (I) and (II), wherein Y, C, R, R, R, and Rare defined herein.