The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 04, 2010

Filed:

Jun. 05, 2008
Applicants:

Stefanie Keil, Hofheim, DE;

Wolfgang Wendler, Selters, DE;

Maike Glien, Wiesbaden, DE;

Jochen Goerlitzer, Frankfurt, DE;

Karen Chandross, Somerset, NJ (US);

Daniel G. Mcgarry, Branchburg, NJ (US);

Jean Merrill, Whippany, NJ (US);

Patrick Bernardelli, Villepreux, FR;

Baptiste Ronan, Clamart, FR;

Corinne Terrier, Livry Gargan, FR;

Inventors:

Stefanie Keil, Hofheim, DE;

Wolfgang Wendler, Selters, DE;

Maike Glien, Wiesbaden, DE;

Jochen Goerlitzer, Frankfurt, DE;

Karen Chandross, Somerset, NJ (US);

Daniel G. McGarry, Branchburg, NJ (US);

Jean Merrill, Whippany, NJ (US);

Patrick Bernardelli, Villepreux, FR;

Baptiste Ronan, Clamart, FR;

Corinne Terrier, Livry Gargan, FR;

Assignee:

Sanofi-Aventis Deutschland GmbH, Frankfurt am Main, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4245 (2006.01); A61K 31/422 (2006.01); A61K 31/427 (2006.01); C07D 277/20 (2006.01); C07D 271/07 (2006.01); C07D 263/30 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to oxadiazolones and to their physiologically acceptable salts and physiologically functional derivatives showing peroxisome proliferator activator receptor (PPAR) delta agonist activity comprising compounds of formula I, in which the R1-R7 substituents as well as the U, V, W, X Y and z radicals are as defined herein, and their physiologically acceptable salts and processes for their preparation. The compounds are suitable for the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders as well as of disorders in which insulin resistance is involved; neurodegenerative diseases and/or demyelinating disorders of the central and peripheral nervous systems and/or neurological diseases involving neuro-inflammatory processes and/or other peripheral neuropathies.


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