The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 04, 2010
Filed:
Mar. 26, 2008
Stefanie Keil, Frankfurt am Main, DE;
Matthias Urmann, Frankfurt am Main, DE;
Patrick Bernardelli, Paris, FR;
Maike Glien, Frankfurt am Main, DE;
Wolfgang Wendler, Frankfurt am Main, DE;
Karen Chandross, Somerset, NJ (US);
Lan Lee, Pluckemin Park, NJ (US);
Stefanie Keil, Frankfurt am Main, DE;
Matthias Urmann, Frankfurt am Main, DE;
Patrick Bernardelli, Paris, FR;
Maike Glien, Frankfurt am Main, DE;
Wolfgang Wendler, Frankfurt am Main, DE;
Karen Chandross, Somerset, NJ (US);
Lan Lee, Pluckemin Park, NJ (US);
Sanofi-Aventis, Paris, FR;
Abstract
The inventive compounds of the present invention are comprised of phenyl and pyridinyl-1,2,4-oxadiazolone derivatives and their physiologically acceptable salts and functional derivatives that are shown to provide peroxisome proliferator activator receptor (PPARdelta) agonist activity. The compounds of the present invention are comprised of the formula: wherein the substituents R1-R5 and R7-R10 are defined herein. The compounds are therapeutically effective in the regulation and modulation of lipid and carbohydrate metabolism in mammals and are thus suitable for the treatment of diseases such as type-2 diabetes, atherosclerosis, cardiovascular disorders and the like.