The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 04, 2010
Filed:
Oct. 24, 2006
Swen Hoelder, Constance, DE;
Karl Schoenafinger, Alzenau, DE;
David William Will, Kriftel, DE;
Hans Matter, Langenselbold, DE;
Guenter Mueller, Sulzbach, DE;
Martin Bossart, Frankfurt, DE;
Swen Hoelder, Constance, DE;
Karl Schoenafinger, Alzenau, DE;
David William Will, Kriftel, DE;
Hans Matter, Langenselbold, DE;
Guenter Mueller, Sulzbach, DE;
Martin Bossart, Frankfurt, DE;
Sanofi-Aventis Deutschland GmbH, Frankfurt am Main, DE;
Abstract
The present invention relates to pyridazinone compounds and their derivatives according to the general formula (I), with the substituents X, Rand Rdefined herein, as well as their physiologically acceptable salts, methods for producing these compounds and their use as pharmaceuticals. These compounds are kinase inhibitors, in particular inhibitors of the kinase GSK-3β (glycogen synthase kinase-3β) which are useful in the treatment of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, strokes, cranial and spinal traumas and peripheral neuropathies, obesity, metabolic diseases, type II diabetes, essential hypertension, atherosclerotic cardiovascular diseases, polycystic ovary syndrome and syndrome X or immunodeficiency.