The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 04, 2010

Filed:

Sep. 01, 2006
Applicants:

Dirk Mayer, Menlo Park, CA (US);

Yakir Levin, Palo Alto, CA (US);

Daniel Spielman, Menlo Park, CA (US);

Ralph Eugene Hurd, Milpitas, CA (US);

Inventors:

Dirk Mayer, Menlo Park, CA (US);

Yakir Levin, Palo Alto, CA (US);

Daniel Spielman, Menlo Park, CA (US);

Ralph Eugene Hurd, Milpitas, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 24/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method of imaging the individual components of systems with sparse spectra using magnetic resonance imaging including the steps of a) exciting nuclei of labeled components using a MRI pulse sequence, b) selecting a proper spectral window to avoid/minimize signal overlap of aliased frequency components. In step a) preferably a spiral chemical shift imaging (spCSI) sequence is employed. In a preferred embodiment, hyperpolarized nuclei ofC are used for labeling in a pyruvate substrate with metabolites of lacatate, alanine, and bicarbonate.


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