The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 04, 2010

Filed:

Jun. 27, 2007
Applicants:

John G. Tew, Mechanicsville, VA (US);

Mohey Eldin M. El Shikh, Richmond, VA (US);

Inderpal Singh, Oviedo, FL (US);

Eric Mishkin, Winter Springs, FL (US);

Donald Drake, Iii, Orlando, FL (US);

Haifeng Song, Ellicott City, MD (US);

William L Warren, Orlando, FL (US);

Inventors:

John G. Tew, Mechanicsville, VA (US);

Mohey Eldin M. El Shikh, Richmond, VA (US);

Inderpal Singh, Oviedo, FL (US);

Eric Mishkin, Winter Springs, FL (US);

Donald Drake, III, Orlando, FL (US);

Haifeng Song, Ellicott City, MD (US);

William L Warren, Orlando, FL (US);

Assignees:

Vax Design Corp., Orlando, FL (US);

Virginia Commonwealth University, Richmond, VA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/02 (2006.01); C12N 5/16 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to methods for constructing and using in vivo and in vitro models of aspects of human immunity and, in particular, construction of a human immune system model for the testing of, for example, vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals. The present invention comprises both in vivo and in vitro models of aspects of human immunity that are useful for assessing the interaction of substances with the immune system, and thus can be used to accelerate and improve the accuracy and predictability of, for example, vaccine, drug, biologic, immunotherapy, cosmetic and chemical development. The invention is also useful for the generation of human monoclonal and polyclonal antibodies.


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