The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 04, 2010
Filed:
Sep. 11, 2006
Sergey Borisovich Zotchev, Trondheim, NO;
Olga Nikolayivna Sekurova, Trondheim, NO;
Espen Fjærvik, Trondheim, NO;
Trygve Brautaset, Trondheim, NO;
Arne Reidar Strøm, Trondheim, NO;
Svein Valla, Vikhamar, NO;
Trond Erling Ellingsen, Ranheim, NO;
Håvard Sletta, Trondheim, NO;
Ole-martin Gulliksen, Oslo, NO;
Sergey Borisovich Zotchev, Trondheim, NO;
Olga Nikolayivna Sekurova, Trondheim, NO;
Espen Fjærvik, Trondheim, NO;
Trygve Brautaset, Trondheim, NO;
Arne Reidar Strøm, Trondheim, NO;
Svein Valla, Vikhamar, NO;
Trond Erling Ellingsen, Ranheim, NO;
Håvard Sletta, Trondheim, NO;
Ole-Martin Gulliksen, Oslo, NO;
Sinvent AS, Trondheim, NO;
Abstract
The invention provides a nucleic acid molecule comprising: (a) a nucleotide sequence as shown in SEQ ID No. 35; or (b) a nucleotide sequence which is the complement of SEQ ID No. 35; or (c) a nucleotide sequence which is degenerate with SEQ ID No. 35; or (d) a nucleotide sequence hybridising under conditions of high stringency to SEQ ID No. 35, to the complement of SEQ ID No. 35, or to a hybridisation probe derived from SEQ ID No. 35 or the complement thereof; or (e) a nucleotide sequence having at least 80% sequence identity with SEQ ID No. 35; or (f) a nucleotide sequence having at least 65% sequence identity with SEQ ID No. 35 wherein said sequence preferably encodes or is complementary to a sequence encoding a nystatin PKS enzyme or a part thereof. Also provided are part of such molecules and polypeptides (and parts thereof) encoded by such a nucleic acid molecule, and the use of such molecules and polypeptides in facilitating nystatin biosynthesis and in the synthesis of nystatin derivatives and novel polyketide as macrolide structures.