The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 04, 2010
Filed:
May. 08, 2009
Reiner L. Gentz, Belo Horizonte, BR;
Reinhard Ebner, Gaithersburg, MD (US);
Guo-liang Yu, Berkeley, CA (US);
Steven M. Ruben, Brookeville, MD (US);
Jian NI, Germantown, MD (US);
Ping Feng, Germantown, MD (US);
Reiner L. Gentz, Belo Horizonte, BR;
Reinhard Ebner, Gaithersburg, MD (US);
Guo-Liang Yu, Berkeley, CA (US);
Steven M. Ruben, Brookeville, MD (US);
Jian Ni, Germantown, MD (US);
Ping Feng, Germantown, MD (US);
Human Genome Sciences, Inc., Rockville, MD (US);
Abstract
The present invention relates to novel Tumor Necrosis Factor Receptor proteins. In particular, isolated nucleic acid molecules are provided encoding the human TNFR-6α & -6β proteins. TNFR-6α & -6β polypeptides and antibodies that bind TNFR-6α & -6β polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of TNFR-6α & -6β activity. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating immune system-related disorders.