The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 27, 2010

Filed:

Nov. 02, 2006
Applicants:

Xiaodong Wang, Chapel Hill, NC (US);

Alan Fulp, Willow Springs, NC (US);

Brian Marron, Durham, NC (US);

Serge Beaudoin, Cary, NC (US);

Darrick Seconi, Cary, NC (US);

Mark Suto, Chapel Hill, NC (US);

Inventors:

Xiaodong Wang, Chapel Hill, NC (US);

Alan Fulp, Willow Springs, NC (US);

Brian Marron, Durham, NC (US);

Serge Beaudoin, Cary, NC (US);

Darrick Seconi, Cary, NC (US);

Mark Suto, Chapel Hill, NC (US);

Assignee:

Icagen, Inc., Durham, NC (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/427 (2006.01); C07D 277/46 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds, compositions and methods are provided which are useful in the treatment of diseases through the inhibition of sodium ion flux through voltage-gated sodium channels. More particularly, the invention provides substituted aryl sulfonamides, compositions comprising these compounds, as well as methods of using these compounds or compositions in the treatment of central or peripheral nervous system disorders, particularly pain and chronic pain by blocking sodium channels associated with the onset or recurrence of the indicated conditions. The compounds, compositions and methods of the present invention are of particular use for treating neuropathic or inflammatory pain by the inhibition of ion flux through a voltage-gated sodium channel.


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