The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 27, 2010

Filed:

Jun. 22, 2005
Applicants:

Murray D. Bailey, Pierrefonds, CA;

Punit Bhardwaj, Laval, CA;

Pasquale Forgione, Montreal, CA;

Elise Ghiro, Laval, CA;

Nathalie Goudreau, St. Laurent, CA;

Teddy Halmos, Laval, CA;

Montse Llinas-brunet, Dollard-des-Ormeaux, CA;

Marc-andre Poupart, Laval, CA;

Jean Rancourt, Laval, CA;

Inventors:

Murray D. Bailey, Pierrefonds, CA;

Punit Bhardwaj, Laval, CA;

Pasquale Forgione, Montreal, CA;

Elise Ghiro, Laval, CA;

Nathalie Goudreau, St. Laurent, CA;

Teddy Halmos, Laval, CA;

Montse Llinas-Brunet, Dollard-des-Ormeaux, CA;

Marc-Andre Poupart, Laval, CA;

Jean Rancourt, Laval, CA;

Assignee:

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/535 (2006.01); C07D 413/00 (2006.01); C07D 401/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to compounds of formula (I) wherein R', R, R, R, R, R, Y, n and m are as defined herein. The compounds are useful for the treatment and prevention of hepatitis C viral infections in mammals by inhibiting HCV NS3 protease. The invention further relates to azalactone compounds of the formula (III) which can be reacted with an amide anion to produce the compounds of formula (I).


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