The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 27, 2010

Filed:

Jul. 28, 2008
Applicants:

Michael Sotirios Malamas, Jamison, PA (US);

Ping Zhou, Plainsboro, NJ (US);

William Floyd Fobare, Lawrenceville, NJ (US);

William Ronald Solvibile, East Windsor, NJ (US);

Iwan Suwandi Gunawan, Somerset, NJ (US);

James Joseph Erdei, Philadelphia, PA (US);

Yinfa Yan, Bedminister, NJ (US);

Patrick Michael Andrae, Jamesburg, NJ (US);

Dominick Anthony Quagliato, Bridgewater, NJ (US);

Inventors:

Michael Sotirios Malamas, Jamison, PA (US);

Ping Zhou, Plainsboro, NJ (US);

William Floyd Fobare, Lawrenceville, NJ (US);

William Ronald Solvibile, East Windsor, NJ (US);

Iwan Suwandi Gunawan, Somerset, NJ (US);

James Joseph Erdei, Philadelphia, PA (US);

Yinfa Yan, Bedminister, NJ (US);

Patrick Michael Andrae, Jamesburg, NJ (US);

Dominick Anthony Quagliato, Bridgewater, NJ (US);

Assignee:

Wyeth LLC, Madison, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4178 (2006.01); A61K 31/4439 (2006.01); A61K 31/506 (2006.01); C07D 403/14 (2006.01); C07D 401/14 (2006.01); C07D 233/88 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a 2-amino-5-heteroaryl-5-phenylimidazolone compound of formula I The present invention also provides methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and neurofibrillary tangles.


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