The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 27, 2010

Filed:

Aug. 14, 2002
Applicants:

Alain Delcayre, San José, CA (US);

Jean-bernard Le Pecq, Menlo Park, CA (US);

Inventors:

Alain Delcayre, San José, CA (US);

Jean-Bernard Le Pecq, Menlo Park, CA (US);

Assignee:

Exothera L.L.C., Menlo Park, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/70 (2006.01); C12N 15/74 (2006.01); C12N 15/09 (2006.01); A61N 63/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to compositions and methods for selectively expressing a polypeptide in a membrane vesicle. The invention also relates to genetic constructs and recombinant cells suitable to produce such membrane vesicles. This invention also relates to such functionalized membrane vesicles as well as to methods of making antibodies, methods of producing or regulating an immune response as well as to methods of screening or identifying binding partners using the same. The invention more particularly uses lactadherin or portions thereof to selectively express polypeptides in membrane vesicles, of natural or synthetic origin. This invention can be used in experimental, research, therapeutic, prophylactic or diagnostic areas.


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