The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 27, 2010
Filed:
Jan. 24, 2005
Ian Hector Frazer, St Lucia, AU;
Jian Zhou, Jindalee, AU;
Xiao Yi Sun, Legal Representative, Jindalee, AU;
Ian Hector Frazer, St Lucia, AU;
Jian Zhou, Jindalee, AU;
Xiao Yi Sun, legal representative, Jindalee, AU;
The University of Queensland, Queensland, AU;
Abstract
A method is disclosed for determining the translational efficiency of an individual codon in a cell. The method includes introducing into the cell a synthetic construct including a reporter polynucleotide fused in frame with a tandem repeat of the individual codon, wherein the reporter polynucleotide encodes a reporter protein, and wherein the synthetic construct is operably linked to a regulatory polynucleotide; and measuring expression of the reporter protein in the cell to determine the translational efficiency of the codon.