The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 27, 2010
Filed:
Oct. 19, 2007
Applicants:
Se-chang Kwon, Seoul, KR;
Sung-youb Jung, Seoul, KR;
Sung-min Bae, Seoul, KR;
Gwan-sun Lee, Seoul, KR;
Inventors:
Se-Chang Kwon, Seoul, KR;
Sung-Youb Jung, Seoul, KR;
Sung-Min Bae, Seoul, KR;
Gwan-Sun Lee, Seoul, KR;
Assignee:
Hanmi Pharm. Co., Ltd, Hwaseong-Gun, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/00 (2006.01); C07K 14/435 (2006.01); C07K 14/46 (2006.01); C07K 14/47 (2006.01); C07K 14/475 (2006.01); C07K 14/52 (2006.01); C07K 14/53 (2006.01); C07K 14/535 (2006.01); C12N 15/09 (2006.01); C12N 15/11 (2006.01); C12N 15/12 (2006.01); C12N 15/19 (2006.01); C12N 15/27 (2006.01); C12N 15/63 (2006.01); C12N 15/70 (2006.01); C12N 15/72 (2006.01);
U.S. Cl.
CPC ...
Abstract
A modified human granulocyte-colony stimulating factor (hG-CSF) is produced by culturing a microorganism transformed with an expression vector comprising a gene encoding a modified hG-CSF to produce and secrete the modified hG-CSF to periplasm, said modified hG-CSF being obtained by replacing at least one of the 1st, 2nd, 3rd and 17th amino acids of wild-type hG-CSF (SEQ ID NO: 2) with other amino acid.