The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 27, 2010
Filed:
Feb. 27, 2004
Peter L. Collins, Kensington, MD (US);
Stephane Biacchesi, Bethesda, MD (US);
Ursula Buchholz, Bethesda, MD (US);
Mario H. Skiadopoulos, Potomac, MD (US);
Brian R. Murphy, Bethesda, MD (US);
Peter L. Collins, Kensington, MD (US);
Stephane Biacchesi, Bethesda, MD (US);
Ursula Buchholz, Bethesda, MD (US);
Mario H. Skiadopoulos, Potomac, MD (US);
Brian R. Murphy, Bethesda, MD (US);
Abstract
Recombinant HMPV (rHMPV) and related immunogenic compositions and methods are provided. The rHMPVs, including chimeric and chimeric HMPV vectors viruses, provided according to the current disclosure are infectious and attenuated in permissive mammalian subjects, including humans. The rHMPVs are useful in immunogenic compositions for eliciting an immune response against HPIV, against one or more non-HMPV pathogens, or against a HMPV and a non-HMPV pathogen. Also provided are isolated polynucleotide molecules and vectors incorporating a recombinant HMPV genome or antigenome.