The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 20, 2010
Filed:
Apr. 11, 2006
Mikhail Chafeev, Burnaby, CA;
Nagasree Chakka, Burnaby, CA;
Sultan Chowdhury, Scarborough, CA;
Robert Fraser, North Vancouver, CA;
Jianmin Fu, Coquitlam, CA;
Duanjie Hou, Burnaby, CA;
Tom Hsieh, Burnaby, CA;
Rajender Kamboj, Burnaby, CA;
Shifeng Liu, Port Coquitlam, CA;
Vandna Raina, Burnaby, CA;
Mehran Seid Bagherzadeh, North Vancouver, CA;
Jianyu Sun, Richmond, CA;
Shaoyi Sun, Coquitlam, CA;
Serguei Sviridov, Burnaby, CA;
Mikhail Chafeev, Burnaby, CA;
Nagasree Chakka, Burnaby, CA;
Sultan Chowdhury, Scarborough, CA;
Robert Fraser, North Vancouver, CA;
Jianmin Fu, Coquitlam, CA;
Duanjie Hou, Burnaby, CA;
Tom Hsieh, Burnaby, CA;
Rajender Kamboj, Burnaby, CA;
Shifeng Liu, Port Coquitlam, CA;
Vandna Raina, Burnaby, CA;
Mehran Seid Bagherzadeh, North Vancouver, CA;
Jianyu Sun, Richmond, CA;
Shaoyi Sun, Coquitlam, CA;
Serguei Sviridov, Burnaby, CA;
Xenon Pharmaceuticals Inc., Burnaby, BC, CA;
Abstract
This invention is directed to spiro-oxindole compounds of formula (I): wherein k, j, Q, R, R, R, R, R, R, R, R, and Rare as defined herein, as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof; or a pharmaceutically acceptable salt, solvate or prodrug thereof, which are useful for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain. Pharmaceutical compositions comprising the compounds and methods of preparing and using the compounds are also disclosed.