The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 20, 2010

Filed:

Oct. 11, 2005
Applicants:

Philip Cornwall, Leicestershire, GB;

David Simon Ennis, Leicestershire, GB;

Melvyn Edward Giles, Leicestershire, GB;

Jacob Robert James Perkins, Leicestershire, GB;

Shelly Louise Jenkin, Bristol, GB;

Jeremy Stephen Parker, Bristol, GB;

Bharti Patel, Bristol, GB;

Inventors:

Philip Cornwall, Leicestershire, GB;

David Simon Ennis, Leicestershire, GB;

Melvyn Edward Giles, Leicestershire, GB;

Jacob Robert James Perkins, Leicestershire, GB;

Shelly Louise Jenkin, Bristol, GB;

Jeremy Stephen Parker, Bristol, GB;

Bharti Patel, Bristol, GB;

Assignee:

AstraZeneca AB, Sodertalje, SE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/415 (2006.01); C07D 231/38 (2006.01);
U.S. Cl.
CPC ...
Abstract

A process for making a compound of formula (I), said process comprising a) reacting a compound of formula (II) with: i) a compound of formula (III) by nucleophilic aromatic substitution of Xand ii) a compound of formula (IV) for example by nucleophilic aromatic substitution b) where necessary, converting Xto a carboxylic acid; and c) coupling of the carboxylic acid group to an appropriate heterocyclic amine; wherein all variables are as defined in the description.


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