The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 20, 2010

Filed:

Dec. 23, 2004
Applicants:

Patrick Soon-shiong, Los Angeles, CA (US);

Neil P. Desai, Santa Monica, CA (US);

Chunlin Tao, Beverly Hills, CA (US);

Cheng Zhi Yu, San Diego, CA (US);

Inventors:

Patrick Soon-Shiong, Los Angeles, CA (US);

Neil P. Desai, Santa Monica, CA (US);

Chunlin Tao, Beverly Hills, CA (US);

Cheng Zhi Yu, San Diego, CA (US);

Assignee:

Abraxis BioScience, LLC, Los Angeles, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4745 (2006.01); C07D 491/22 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is related to 10,20-di-O ester derivatives of camptothecin and pharmaceutical formulations thereof. The compounds and pharmaceutical formulations of the present invention possess increased biological life span and bioavailability and reduced toxicity, while maintaining anti-cancer activity.


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