The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 20, 2010

Filed:

Oct. 06, 2005
Applicants:

Anette Gundertofte, Frederiksberg, DK;

Anker Steen Jorgensen, Copenhagen, DK;

Gita Camilla Tejlgaard Kampen, Naerum, DK;

Henrik Sune Andersen, Kgs. Lyngby, DK;

Inge Thoger Christensen, Lyngby, DK;

Kilburn Paul John, Haslev, DK;

Inventors:

Anette Gundertofte, Frederiksberg, DK;

Anker Steen Jorgensen, Copenhagen, DK;

Gita Camilla Tejlgaard Kampen, Naerum, DK;

Henrik Sune Andersen, Kgs. Lyngby, DK;

Inge Thoger Christensen, Lyngby, DK;

Kilburn Paul John, Haslev, DK;

Assignee:

High Point Pharmaceuticals, LLC, High Point, NC (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/55 (2006.01); A61K 31/497 (2006.01); A61K 31/454 (2006.01); A61K 31/403 (2006.01); C07D 223/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

A novel class of compounds of the general formula (I), their use in therapy, pharmaceutical compositions comprising the compounds, as well as their use in the manufacture of medicaments are described. The present compounds modulate the activity of 11β-hydroxy-steroid dehydrogenase type 1 (11βHSD1) and are accordingly useful in the treatment of diseases in which such a modulation is beneficial, e.g. the metabolic syndrome.


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