The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 20, 2010
Filed:
Aug. 19, 2003
Louis A. Pena, Poquott, NY (US);
Paul O. Zamora, Gaithersburg, MD (US);
Xinhua Lin, Plainview, NY (US);
John D. Glass, Shoreham, NY (US);
Louis A. Pena, Poquott, NY (US);
Paul O. Zamora, Gaithersburg, MD (US);
Xinhua Lin, Plainview, NY (US);
John D. Glass, Shoreham, NY (US);
BioSurface Engineering Technologies, Inc., Rockville, MD (US);
Brookhaven Science Associates, Upton, NY (US);
Abstract
The invention provides synthetic heparin-binding growth factor analogs having at least one peptide chain, and preferably two peptide chains branched from a dipeptide branch moiety composed of two trifunctional amino acid residues, which peptide chain or chains bind a heparin-binding growth factor receptor and are covalently bound to a non-signaling peptide that includes a heparin-binding domain, preferably by a linker, which may be a hydrophobic linker. The synthetic heparin-binding growth factor analogs are useful as pharmaceutical agents, soluble biologics or as surface coatings for medical devices.