The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 20, 2010
Filed:
Oct. 13, 2006
Richard Beliveau, Ile Des Soeurs, CA;
Michel Demeule, Longueuil, CA;
Joseph Yang, North Delta, CA;
Malcolm L. Kennard, North Vancouver, CA;
Reinhard Gabathuler, San Rafael, CA (US);
Richard Beliveau, Ile Des Soeurs, CA;
Michel Demeule, Longueuil, CA;
Joseph Yang, North Delta, CA;
Malcolm L. Kennard, North Vancouver, CA;
Reinhard Gabathuler, San Rafael, CA (US);
Raptor Pharmaceuticals Inc., Novato, CA (US);
Abstract
This invention provides conjugates of therapeutic or active agents with melanotransferrin or with other ligands of a melanotransferrin receptor, melanotransferrin receptor modulators, and related compositions and methods for modulating blood-brain barrier transport by providing methods of screening and selecting such conjugates, ligands, and modulators in vitro and in vivo, and methods of use of such conjugates, modulators and ligands in diagnosis and the treatment of diseases, including particularly diseases of the central nervous system or lysosomal storage diseases.