The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 20, 2010
Filed:
Jul. 28, 2006
Horst Wähling, Huddinge, SE;
Bertil Samuelsson, Huddinge, SE;
Horst Wähling, Huddinge, SE;
Bertil Samuelsson, Huddinge, SE;
Medivir AB, Huddinge, SE;
Abstract
Compounds of the formula (I): and N-oxides, salts and stereoisomers thereof wherein A is OR, NHS(═O)R, NHR, NRaRb, C(═O)NHRor C(═O)NRaRb wherein; Ris hydrogen, C-Calkyl, C-Calkylenecarbocyclyl, C-Calkyleneheterocyclyl; Ris C-Calkyl, C-Calkylenecarbocyclyl, C-Calkyleneheterocyclyl or NRaRb; Ris C-Calkyl, C-Calkylenecarbocyclyl, C-Calkyleneheterocyclyl, —OC-Calkyl, —OC-Calkylenecarbocyclyl, —OC-Calkyleneheterocyclyl; wherein any alkyl, carbocyclyl or heterocycylyl in R, Ror Rare optionally substituted p is independently 1 or 2; n is 3, 4, 5 or 6; denotes an optional double bond; Rq is H or when L is CRz, Rq can also be C-Calkyl; Ry and Ry' are independently C-Calkyl; L is N or CRz; Rz is H or forms a double bond with the asterisked carbon; W is —CH—, —O—, —OC(═O)NH—, —OC(═O)—, —S—, —NH—, —NRa, —NHS(═O)—, —NHC(=0)NH— or —NHC(═O)—, —NHC(═S)NH— or a bond; Ris an optionally substituted ring system containing 1 or 2 saturated, partially saturated or unsaturated carbo or heterocyclic rings have utility in the inhibition of NS-3 serine proteases, such as flavivirus infections.