The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 20, 2010

Filed:

Nov. 07, 2005
Applicants:

Robert Kisilevsky, Kingston, CA;

Shui-pang Tam, Kingston, CA;

John B. Ancsin, Kingston, CA;

Zongchao Jia, Kingston, CA;

Inventors:

Robert Kisilevsky, Kingston, CA;

Shui-Pang Tam, Kingston, CA;

John B. Ancsin, Kingston, CA;

Zongchao Jia, Kingston, CA;

Assignee:

Queens's University at Kingston, Kingston, Ontario, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/10 (2006.01); C07K 7/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

Peptides and mimetics of selected domains of mammalian serum amyloid A isoform 2.1 (SAA2.1) and compounds and compositions thereof are provided that enhance the effect on macrophage cholesterol ester hydrolase activity and/or inhibit acyl CoA:cholesterol acyl transferase activity. Methods of using these compositions in the treatment and/or prevention of atherosclerosis as well as coronary heart disease and cardiovascular disease are also provided.


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