The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 20, 2010
Filed:
Nov. 02, 2004
Albert S. Baldwin, Chapel Hill, NC (US);
James C. Cusack, Chapel Hill, NC (US);
Marty W. Mayo, Durham, NC (US);
Cun-yu Wang, Chapel Hill, NC (US);
Albert S. Baldwin, Chapel Hill, NC (US);
James C. Cusack, Chapel Hill, NC (US);
Marty W. Mayo, Durham, NC (US);
Cun-Yu Wang, Chapel Hill, NC (US);
The University of North Carolina at Chapel Hill, Chapel Hill, NC (US);
Abstract
The use of NF-κB inhibitors to enhance the cytotoxic effects of chemotherapy or radiation therapy in the treatment of neoplastic conditions is described. When chemotherapeutic compounds and radiation activate NF-κB within cells, the cells are more resistant to the cytotoxic effects of these treatments. Inhibition of NF-κB activation is disclosed to provide a method to improve the efficacy of these cancer therapies.