The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 20, 2010
Filed:
Jan. 19, 2004
Bernard Brulez, Bourbonne les Baines, FR;
Jacques-philippe Laboureau, Le Tignet, FR;
Veronique Migonney, Eaubonne, FR;
Mihaela Ciobanu, Iasi, RO;
Graciela Pavon-djavid, Puteaux, FR;
Alain Siove, Sousy Sous Montmorency, FR;
Bernard Brulez, Bourbonne les Baines, FR;
Jacques-Philippe Laboureau, Le Tignet, FR;
Veronique Migonney, Eaubonne, FR;
Mihaela Ciobanu, Iasi, RO;
Graciela Pavon-Djavid, Puteaux, FR;
Alain Siove, Sousy Sous Montmorency, FR;
LARS- Laboratoire d'Application et de Recherche Scientifique, Arc-sur-Tille, FR;
Abstract
Biomimetic artificial prostheses which are made from polyester, such as polyethylene terephthalate, and a method for the biomimetic functionalization of such prostheses. The method includes a step involving the grafting of biologically-active polymers or copolymers to the polyester surface of the prostheses, the grafting step consisting of the peroxidation of the surface by ozonation followed by a step including the radical polymerization of a solution of at least one monomer. The method also includes an optional step consisting in impregnating the prostheses with type I and/or II collagen and/or fibronectins. The prostheses thus obtained enable a normal and uniform regrowth of the fibroblasts, thereby significantly improving the biological integration of such polyester prostheses.