The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 13, 2010
Filed:
Dec. 20, 2006
Jae-sun Kim, Suwon-si, KR;
Nam Ho Kim, Seongnam-si, KR;
Nam Kyu Lee, Suwon-si, KR;
Jin Young Lee, Suwon-si, KR;
Jae-Sun Kim, Suwon-si, KR;
Nam Ho Kim, Seongnam-si, KR;
Nam Kyu Lee, Suwon-si, KR;
Jin Young Lee, Suwon-si, KR;
SK Chemicals Co., Ltd., Gyeonggi-do, KR;
Abstract
The present invention relates to a process for the preparation of S-(+)-clopidogrel by an optical resolution and, more particularly, to a process for the preparation of S-(+)-clopidogrel represented by the following formula 1 with high optical purity by converting a clopidogrel racemic carboxylic acid into a diastereomeric salt using a (+)-cinchonine for optical resolution, extracting an S-(+)-clopidogrel carboxylic acid from the diastereomeric salt using a suitable solvent under an acidic condition and then reacting the S-(+)-clopidogrel carboxylic acid with methanol.