The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 13, 2010
Filed:
Mar. 13, 2006
Keigo Tanaka, Tsukuba, JP;
Satoshi Inoue, Tsukuba, JP;
Daisuke Ito, Tsukuba, JP;
Norio Murai, Tsukuba, JP;
Yosuke Kaburagi, Tsukuba, JP;
Shuji Shirotori, Tsukuba, JP;
Shuichi Suzuki, Tsukuba, JP;
Yoshiaki Ohashi, Tsukuba, JP;
Keigo Tanaka, Tsukuba, JP;
Satoshi Inoue, Tsukuba, JP;
Daisuke Ito, Tsukuba, JP;
Norio Murai, Tsukuba, JP;
Yosuke Kaburagi, Tsukuba, JP;
Shuji Shirotori, Tsukuba, JP;
Shuichi Suzuki, Tsukuba, JP;
Yoshiaki Ohashi, Tsukuba, JP;
Eisai R&D Management Co., Ltd., Tokyo, JP;
Abstract
The present invention provides compounds which are useful as safe substitutes for the organotin reagent used in coupling reaction for the oxymethylation of aromatic rings, such as alkoxymethylation or hydroxymethylation, with a palladium catalyst and which can dispense with chromatographic purification with silica gel in the production and are suitable for mass production; and compounds applicable even to the oxymethylation of aromatic ring substrates which do not permit coupling reaction by conventional technique or have low reactivity.