The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 13, 2010
Filed:
Apr. 11, 2008
Marc Diamond, San Francisco, CA (US);
Jeremy Jones, San Francisco, CA (US);
Adam Renslo, Oakland, CA (US);
Marc Diamond, San Francisco, CA (US);
Jeremy Jones, San Francisco, CA (US);
Adam Renslo, Oakland, CA (US);
Regents of the University of California, Oakland, CA (US);
Abstract
The present invention provides a method of inhibiting an androgen receptor by administering a compound of Formula I: or a compound of Formula II: wherein R, R, Rand Rare each independently hydrogen or Calkyl. Ris absent or is hydrogen, Calkyl or Calkyl-OH. Ris hydrogen, Calkyl or —NRR. Rand Rare each independently hydrogen or Calkyl, or are combined with the nitrogen to which they are attached to form a heterocycloalkyl having from 5 to 7 ring members. L is a linker of Calkylene, Calkenylene, Calkynylene or Ccycloalkylene. The compounds of Formula I include the salts, hydrates and prodrugs thereof. Each Ris H, Calkyl, —OH or —O—Calkyl. The compounds of Formulas I and II include the salts, hydrates and prodrugs thereof. By administering the compound of Formula I or II, the method inhibits the androgen receptor.