The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 13, 2010

Filed:

Dec. 21, 2007
Applicants:

James Mccabe, Macclesfield, GB;

Gary Peter Tomkinson, Macclesfield, GB;

Inventors:

James McCabe, Macclesfield, GB;

Gary Peter Tomkinson, Macclesfield, GB;

Assignee:

AstraZeneca AB, Sodertalje, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/00 (2006.01); A61K 31/397 (2006.01); A61K 31/00 (2006.01); A01N 43/58 (2006.01); A61K 31/50 (2006.01); A01N 43/60 (2006.01); A61K 31/495 (2006.01); A61K 31/497 (2006.01); A01N 43/56 (2006.01);
U.S. Cl.
CPC ...
Abstract

A novel crystalline form of 3-{[5-(azetidin-1-ylcarbonyl)pyrazin-2-yl]oxy}-5-[(1-methylethyl)oxy]-N-1H-pyrazol-3-ylbenzamide is described in the specification. This compound is a glucokinase (GLK or GK) activator and useful as a pharmaceutical agent in the treatment or prevention of a disease or medical condition mediated through GLK, leading to a decreased glucose threshold for insulin secretion. Processes for the manufacture of the crystalline form, pharmaceutical compositions comprising the crystalline form and the use of the crystalline form in medical treatment are also described.


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