The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 13, 2010
Filed:
Jan. 21, 2005
Applicants:
Claude V. Maina, West Newbury, MA (US);
George Tzertzinis, Cambridge, MA (US);
Sanjay Kumar, Ipswich, MA (US);
Inventors:
Claude V. Maina, West Newbury, MA (US);
George Tzertzinis, Cambridge, MA (US);
Sanjay Kumar, Ipswich, MA (US);
Assignee:
New England Biolabs, Inc., Ipswich, MA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/02 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
Abstract
Compositions and methods are provided for preparing an hsiRNA mixture and for silencing of gene expression in vivo. The composition relates to a mutant RnaseIII. The methods are directed to reacting a preparation of dsRNA with an effective amount of a mutant RNAse III to produce the hsiRNA mixture.