The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 13, 2010

Filed:

Aug. 28, 2003
Applicants:

Kazumori Funatsu, Fukuoka, JP;

Kohji Nakazawa, Fukuoka, JP;

Hiroshi Mizumoto, Fukuoka, JP;

Junji Fukuda, Fukuoka, JP;

Mikitomo Yasutake, Oita, JP;

Inventors:

Kazumori Funatsu, Fukuoka, JP;

Kohji Nakazawa, Fukuoka, JP;

Hiroshi Mizumoto, Fukuoka, JP;

Junji Fukuda, Fukuoka, JP;

Mikitomo Yasutake, Oita, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/12 (2006.01); C12M 3/06 (2006.01); C12N 5/00 (2006.01); C12N 11/04 (2006.01); A61F 2/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

To provide a cell-filled device that is suitable for use in, for example, an implantable or circulation type hybrid artificial organ. In a cell-filled device including hollow fiber membranes whose hollow portions are filled with cells, the hollow fiber membranes have modified cross sections, and a cell aggregate provided in each of the hollow portions has cells formed into two or more layers in arbitrary directions, provided that the distance from an arbitrary point of the cell aggregate to the nearest inner wall of hollow fiber membrane is less than 75 μm. This cell-filled device enables effective use of cells without the necrosis thereof. Further, according to the present invention, there is provided a method of manufacturing the cell-filled device.


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